اختيار اللغة
وحدة البحوث الطبية العلاقات الثقافية شعبة ضمان الجودة و الأداء الجامعي وحدة التعليم الطبي و تطوير المناهج الدراسية لجنة التعضيد شعبة النشاطات الطلابية





تسجيل دخول الطلبة
الرقم الجامعي :
كلمة المرور:

تسجيل دخول التدريسيين
 
اسم التدريسي :
كلمة المرور :



ورشة عمل #2 بعنوان (طريقة توثيق الاجهزة المختبرية)
ورشة عمل #1 بعنوان (الية العمل مع وحدة اعتماد المختبرات)
ندوة ثقافية عن (مفاهيم الجودة واهميتها في التعليم العالي)
اجتماع ضمن مشروع تطوير البنى التحتية
برنامج الجودة الثقافي 2016-2017
منهاج الدراسات العليا

MSc Microbiology

1st Semester

Subjects

Code

Hours/week

Credits

Theory

Practical

1

Bacteriology

MICBac-M1

1

-

1

2

Biostatistics

COMSta-M1

2

-

2

3

English language

ENGEng-M1

1

-

1

4

Immunology

MICImm-M1

2

3

3

5

Molecular biology

MICMol-M1

2

-

2

6

Virology

MICVir-M1

2

3

3

7

Pathology

PATMic-M1

1

-

1

8

Biochemistry

CHMMic-M1

1

-

1

Total

14

2nd Semester

Subjects

Code

Hours/week

Credits

Theory

Practical

1

Bacteriology

MICBac-M2

2

3

3

2

Mycology

MICMyc-M2

1

3

2

3

Parasitology

MICPar-M2

2

3

3

4

Research methodology

COMRme-M2

1

-

1

5

Seminar

MICSem-M2

-

-

-

Total

10

PhD Microbiology

1st Semester

Subjects

Code

Hours/week

Credits

Theory

Practical

1

Bacteriology

MICBac-P1

1

-

1

2

English language

ENGEng-P1

1

-

1

3

Molecular biology

MICMol-P1

2

-

2

4

Parasitology

MICPar-P1

2

3

3

5

Seminar

MICSem-P1

-

-

-

6

Immunology

MICImm-P1

2

3

3

Total

10

2nd Semester

Subjects

Code

Hours/week

Credits

Theory

Practical

1

Bacteriology

MICBac-P2

3

3

4

2

Gene therapy

MICGth-P2

2

-

2

3

Mycology

MICMyc-P2

2

3

3

4

Seminar

MICSem-P2

1

-

1

5

SPSS

CMRSps-P2

1

-

1

6

Virology

MICVir-P2

2

3

3

Total

14

 

Aims of the Study:
The MSc in Medical Microbiology is a one-year full time course designed to provide MSc students with knowledge in two courses, stressing the challenges posed by pathogens and how they shape immune responses.
Objectives of the Study:
Students will learn about clinically relevant pathogens through an introductory module on Medical Microbiology and specialized courses on Bacteriology, Immunology, Virology, Parasitology, Mycology and Molecular biology.
Provision for the development of practical research skills will be offered by each course, preparing the students for Research Projects leading to a dissertation.
Medical Bacteriology:
M.Sc First Course: 1 credit = 1 theory lecture / week

 

Introduction Classification and Taxonomy

1.

Bacteria compared with other microorganisms

2.

Structure of bacterial cell

3.

Sterilization and disinfection

4.

Bacterial nutrition, culture media

5.

Normal,microbial flora of the human body

6.

Growth of Bacteria

7.

Microbial metabolism,energy and biosynthesis

8.

Microbial Genetics

9.

Antimicrobial drugs/ mechanism of action

10.

Antimicrobial drugs/resistance

11.

Bacterial vaccines

12.

Virulence and pathogenesis

13.

Bacterial Toxins

14.

Bacteria Enzymes

15.

M.Sc Second Course:
Credit: 3 units = (2 hrs theory+3 hrs practical)/week

1.

Gram- positive cocci

2.

Gram- negative cocci

3.

Gram- positive rods

4.

Sporulated bacteria/ Gram- positive rods

5.

Gram- negative rods (enteric bacteria)

6.

Pseudo ,Bordetella and Haemophillus.

7.

Brucella spp.

8.

Comma shaped and spiral bacteria

9.

Mycobacteria

10.

Mycoplasma

11.

Chlamydiae

12.

Rickettsiae

13.

Actinomycetes, Nocardia

14.

Treponema

15.

Zonootic Bacteriology

Practical Sessions:

1.

Specimen collection and management

2.

Direct & general examination of specimens.

3.

Antimicrobial susceptibility

4.

Gram- positive cocci

5.

Gram- negative cocci

6.

Gram- positive rods

7.

Gram- negative rods (enteric bacteria)

8.

Comma shaped and spiral bacteria

9.

Brucella, pseudomonas

10.

Mycobacteria

11.

Actinomycetes, Nocardia

12.

Mycoplasma

13.

Chlamydia, Rickettsia Treponema,

Medical Immunology
One course: first
Credit: 3 units = (2 hrs theory+3 hrs practical)/week

1-

Introduction to immune system
-Antigen Ag, Foreign (Pathogen) Antigens
-CD Antigen Markers

2

-B Cell Development
-Generation of B Cells
-Regulation of B Cell Development
-Positive Selection of B Cells
-Negative Selection of B Cells
-B Cell Heterogeneity
Acquired immune response:-Abs

3

-T Cell Development
-Generation of T Cells 
-Positive Selection of T cells
-Negative Selection of T Cells
T Cell Activation
Properties of Effector Cells
Cytotoxic T Cells
Macrophage Activation by Th1 (Inflammatory T) Cells

4-

Complement : Functions, Cascades and Regulationof Function

5-

Cytokines

6-

MHCImmune system cells cooperation

7-

Infection and Immunity

8-

Tumor Immunology

9-

Hypersensitivity typeI, II

10-

Hypersensitivity type III,IV

11-

Autoimmunity Part 1

12-

Autoimmunity Part 2

13-

Immune Deficiency diseases

14-

Transplantation

15-

Vaccines

Practical Sessions:

  1. Introduction
  1. Ab-Ag reaction (precipitation)
  1. Electrophoretic Techniques
  1. Ab-Ag reaction (agglutination)
  1. Ab-Ag reaction (hemagglutination)
  1. Ab-Ag reaction (complement fixation)
  1. Complement system assessment (CH50% and CH100%)
  1. Ab-Ag reaction (ELISA)
  1. Ab-Ag reaction (immunoflourescence testandRIA)
  1. Cell isolation, Cell counting and functional assessment
  1. Immunocytochemistry
  1. Immunohistochemistry
  1. Cross-matching and HLA-typing
  1. In situ Hybridization

 

Medical Virology:
One course: first
Credit: 3 units = (2 hrs theory+3 hrs practical)/ week

  1. General prosperities and classification of viruses
  1. Viral replication and viral genetics
  1. Cultivation of viruses, effect of virus on host cells, pathogenesis of viral disease (acute, chronic, latent, and slow viral infection).
  1. Prevention and treatment of viral infections: interferon, antiviral chemotherapy and viral vaccines.
  1. DNA Viruses, enveloped and non-enveloped.
  1. RNA Enveloped Viruses: Orthomyxoviruses
  1. Paramyxoviruses
  1. Hepatitis Viruses
  1. Rhabdovirus: RNA non-enveloped viruses
  1. Reo, Corona virus, SARS
  1. Retroviruses
  1. Oncogenic viruses

Practical Sessions:

  1. Introduction to Practical Virology
  1. Methods of diagnosis of viral infections
  1. Preparation of tissue culture, clinical specimens’ collection and handling.
  1. Inoculation of clinical sample in tissue culture, in embryo-egg, and in lab. Animals.
  1. Immuno-Electon Microscopy (IEM).
  1. Immunocytochemistry (ICC).
  2. Immunohistochemistry (IHC).
  1. In situ hybridization (ISH).
  1. Polymerase chain reaction (PCR)
  1. Polymerase chain reaction (PCR)
  1. Indirect Methods: Serology.

Medical Parasitology:
One course: Second
Credit: 3 units = (2 hrs theory+3 hrs practical)/ week

  1. Host-parasite origin, adaptation to parasitism, definitions and                                                                   classification.  Fate of parasite and evasion of the immune system, effect of   parasite on the host.
  1. Pathology and pathogenesis of intestinal nematodes.
  1. Anemia in helminth infections with special reference to hookworm anaemia.
  1. Hydatid disease.
  1. Vaccines in Helminthology. V.L.M.  Eosinophilia.
  1. Bladder carcinoma and bilharzia.
  1. Intraspecific variations and epidemiolog
  1. Medical Protozology :Introduction, definitions, classification, origin of parasitism
  1. Entamoebahistolytica, pathogenic free-living amoebae
  1. Giardiasis: pathogenesis of chronic diarrhea and impact on child health and development.
  1. Intraspecific variations, method used and epidemiology.
  1. Vaccination with special reference to malaria and leishmaniasis.
  1. Drug resistance in malaria. AIDS and parasitic infections, a new  concept of parasitic zoonoses
  1. Immunity to protozoal infections.
  2. Congenital Toxoplasmosis.
  1. Medical  Insects

Practical Sessions

  1. Introduction,fecal examination
  1. Enterobius,Trichuris, Strongyloides, Ascaris
  1. Hookworms
  1. Echinococcus  spp.
  1. Trichinella , Filaria, larva migrans,
  1. Schistosoma spp.
  1. Cultivation of helminthes Preservation of helminthes.
  1. Blood film and stool examination
  1. Introduction, faecal examination, Entamoeba. Other amoebae                      
  1. Flagellates, ciliates
  1. Culture methods used in Protozoology.
  1. Leishmania, Trypanosoma.Malaria (Plasmodium)
  1. Preservation of protozoa
  1. Animal inoculation as a method of diagnosis. Staining method.
  1. Medical  Insects

Medical Mycology
Course: one course second
Credits: two units= (1 hr theory + 2 hrs practical sessios) / week

  1. The fungi: An introduction of different pathogenic fungi, their general properties, immunity to fungi & predisposing factors.
  1. Mycetoma; Etiology, Epidemiology & ecology, Clinical manifestations, Pathology & immunology,Treatment, & lab. DX.
  1. Dermatophytosis: Etiology, Epidemiology &ecology, Clinical manifestations, Pathology &Iimmunology,Treatment, & lab. DX.
  1. Candidiasis; Etiology, Epidemiology &Ecology, Clinical manifestations, Pathology &Immunology,Treatment, & lab. DX.
  1. Cryptococcosis; Etiology, Epidemiology & ecology, Clinical manifestations, Pathology & immunology,Treatment, & lab. DX.
  1. Histoplasmosis; Etiology, Epidemiology &ecology, Clinical manifestations, Pathology & immunology,Treatment, & lab. DX.
  1. Sporotrichosis; Etiology, Epidemiology &ecology, Clinical manifestations, Pathology & immunology,Treatment, & lab. DX.
  1. Blastomycosis; Etiology, Epidemiology &ecology, Clinical manifestations, Pathology & immunology,Treatment, & lab. DX.
  1. Miscellaneous Fungi
  1. Mycotoxicosis
  1. Antimycotic Therapy
  1. Topics presented by students

Practical Sessions

  1. An introductory review of the important pathogenic fungi, &How to diagnose these fungi
  1. Data show of the pathogenic agent & The types of lesions it produced.
  1. Data show of the pathogenic agent & The types of lesions it produced.
  1. Data show of the pathogenic agent & The types of lesions it produced.
  1. Data show of the pathogenic agent & The types of lesions it produced.
  1. Data show of the pathogenic agent & The types of lesions it produced.
  1. Data show of the pathogenic agent & The types of lesions it produced.
  1. Data show of the pathogenic agent & The types of lesions it produced.
  1. Data show of the pathogenic agent & The types of lesions it produced.

 

Molecular Biology:
Credits: 2 units: 2 theory lectures /week

  1. Introduction and DNA replication
  1. Gene expression: mechanisms of gene expression and gene expression control (operons)
  1. Microbial genetics:
  2. -Transformation
  3. -Conjugation
  4. -Transduction
  1. Molecular biology applications and tests:
    1. gel electrophoresis
  2. - RFLP
    1. Hybridization techniques
  1. - Gene cloning
  1. PCR: Optimization of PCR
  1. Genetic Mutations
  1. Genetic variations
  1. Cell Cycle
  1. Genetic Check points
  1. Introduction to Cytogenetic
  1. Mitochondrial DNA

 

Postgraduate PhD Curriculum Medical Microbiology Department

Medical Bacteriology:
First Course:
Credit = 1 Credit: 1 theory lecture /week

  1. Taxonomy,classification, Nomenclature &Identification
  1. Bacterial cell
  1. Environmental and Nutritional requirements
  1. Growth and division
  1. Metabolism
  1. Normal flora of human body
  1. Bacterial genetics, cloning and gene expression
  1. Extra chromosomal elements
  1. Mutations and gene transfer
  1. Outbreak investigations and diseases management
  1. Hospital infection
  1. Virulence and pathogenesis
  1. Bacterial toxins
  1. Bacterial antagonism:Bacteriocins
  1. Epidemiology of infectious diseases

 

Second Course:
Credits: 3 credit = (2hr theory lectures+ 2 hr practical)/week

  1. Upper respiratory  tract infection
  1. Lower respiratory  tract infection
  1. Gastro-intestinal system infants
  1. Gastro-intestinal system adults
  1. Genito-urinary system females
  1. Genito-urinary system males.
  1. Microorganisms of skin diseases
  1. Mucous membrane diseases
  1. Infections  of muscle, joints, and bone

Infections of eye

  1. Infections  of  blood
  1. Zoonotic bacterial diseases
  1. Blood  and CSF/  Swabs & soft tissue specimens

 

Practical Sessions

  1. Specimens/Collection & handling of specimens.
  1. Direct & general examination of specimens/ Staining.
  1. Media & Pure culture
  1. Sterilization
  1. Antimicrobial Susceptibility.
  1. General examination & testing for M.O. encountered in the urine.
  1. General examination & testing for M.O. encountered in the stool
  1. General examination & testing for M.O. encountered in the blood
  1. General examination & testing for M.O. encountered in the CSF
  1. General examination & testing for M.O. encountered in the sputum
  1. Swabs (wound, soft tissues, urethra & vaginal).
  1. Genetic probes in diagnostic microbiology

Medical Immunology
First Course:
Credits: 3 credit = (2 hr theory lectures+ 2 hr practical)/week

  1. T-lymphocyte-types activation
  1. T-regulatory and B-regulatory, cross presentation
  1. Dendritic  cells and their role in immune response
  1. Apoptosis
  1. CPG  and their role in immunity
  1. Signal transduction in T & B cells
  1. Heat shock proteins and immune response 
  1. Role of different stress and IR
  1. Endocrine and IS
  1. HLA and diseases
  1. Complement
  1. Immuno-regulation
  1. Vaccination

Practical Sessions:

  1. Ab-Ag reaction (precipitation)
  1. Electrophoretic Techniques
  1. Ab-Ag reaction (agglutination)
  1. Ab-Ag reaction (hemagglutination)
  1. Ab-Ag reaction (complement fixation)
  1. Complement system assessment
  2. (CH50% and CH100%)
  1. Ab-Ag reaction (ELISA)
  1. Ab-Ag reaction (immunoflourescence testandRIA)
  1. Cell isolation, Cell counting and functional assessment
  1. Immunocytochemistry
  1. Immunohistochemistry
  1. Cross-matching and HLA-typing
  1. In situ Hybridization

 

Second Course:
Credit: 1 credit = 1 theory lecture /week

  1. Tumor immunology, basic  theories for arising of tumors
  1. Molecular aspects in cell transformations
  1. Immune surveilence  and tumor escape mechanisms
  1. Tumor markers-adjuvants and immunotherapy for cancers
  1. Autoimmunity-part- I
  1. Autoimmunity-part-II
  1. Mid-term exam
  1. Transplantation-Part- I
  1. Transplantation-Part- II
  1. Hypersensitivity-part –I
  1. Hypersensitivity-part –II
  1. Reproductive immunology
  1. Immunity to infection part –I
  1. Immunity to infection part –II
  1. IDD

Medical Virology
Second Course:

  1. Introduction, definitions in virology and viral replication cycle
  1. Chemical composition of viruses, viral genetics, interactions among viruses
  1. Interferons (as antivirals),

-viral vaccines,    
-antiviral-drugs (mechanisms of action)

  1. DNA enveloped viruses (Herpes viruses)

-Latent viral infections, HSV-1 latent in vestibular ganglia, 
-Human herpes virus 6 in non-neurological diseases, 
-oncogenesis of human herpes virus 8 in Kaposi's sarcoma.

  1. DNA non-enveloped viruses
    1. -Parvovirus B19 (Aplastic anemia and effect on erythrocytes)
    2. -Carcinogenesis in other DNA non-enveloped (human papilloma viruses, polyoma viruses and adenoviruses)
  1. RNA enveloped viruses: Influenza A virus
    1. -General properties of influenza viruses,    -Genetic (mutations)
    2. -Pathology of H1N1 infection
  2. -New trends in H1N1 chemotherapy and vaccination
  1. Pathology and pathogenesis in
    1. -Measles and SSPE (subacutesclerosingpanencephalitis)
    2. -Mumps virus complications and male sterility
    3. -RSV bronchiolitis in children under 2 years of age
    4. -Rotavirus gastroenteritis in children.
  1. Adinoviruses
  1. HEPATITIS VIRUSES

-Properties of hepatitis viruses (HBV and HCV genotypes classification)
-Chronic hepatitis B and C viruses (pathology)
-Role of HBV and HCV in hepatocellular carcinoma

  1. Human Immunodeficiency virus HIV

-General properties and clinical manifestations
-Immuno-pathology and how HIV evades host immune system
-New trends in HIV chemotherapy and vaccination

  1. Reo, Corona virus, SARS
  1. Mechanisms of viral carcinogenesis in

-DNA viruses

    1. -RNA viruses
  1. Viruses of Bacteria (Bacteriophages)

Credits: 3 credit = (2 hr theory lectures+ 2 hr practical)/week

Practical Sessions:

  1. Introduction to Practical Virology
  1. Methods of diagnosis of viral infections
  1. Preparation of tissue culture, Clinical specimens collection and handling:
  1. Inoculation of clinical sample in tissue culture, in embryo-egg, and in lab. Animals.
  1. ImmunoElecton Microscopy (IEM).
  1. Immunocytochemistry (ICC).
  2. Immunohistochemistry (IHC).
  1. In situ hybridization (ISH).
  1. Polymerase chain reaction (PCR) Extraction of N.A.
  1. Polymerase chain reaction (PCR)
  1. Indirect Methods: Serology.
  1. Clinical Applications.
  1. Clinical Applications.

Medical Parasitology
Second Course:
Credits: 3 credit = (2 hr theory lectures+ 2 hr practical)/week


General Parasitology
  1. Definition, Introduction to parasite, Host- parasite relationships ,Source of infection Mode of infection ,Attributes of pathogenic parasites,Attributes of host that resist infection,Direct physical & chemical changes,Tissue damage by immunological mechanism,Laboratorydiagnosis Classification of parasite                                                                                    
  1. Introduction to helminthes:Nematodes
  2. General features,Classification
  3. Enterobiusvermicularis ,Trichuristrichiura ,Ascarislumbricoides ,Strongyloidesstercoralis
  1. Hook worm :Visceral larva migrans ,Cutaneous larvae migrans
  2. Toxocaracanis,Dracunculusmedinensis
  3. Angiostrongyluscantonensis ,Gnathostoma spp.
  4. Capillaria spp.,Trichinellaspiralis
  1. Trematodes :General features ,Classification
  2. Schistasomiasis,Fasciola hepatica, F. buski
  3. Paragonimuswesermani.
  1. Introduction to Protozoa ,General features
  2. Classification
  1. Amoeba:Entamoebahistolytica
  2. Non-pathogenic amebae :
  3. E. dispar,E. hartmanni ,E. coli,E. gingivalis ,Endolimax nana, Ioddamoebabuetschlii
  1. Opportunistic amoeba :
  2. N  aegleriafowleri ,Acanthamoeba  spp.
  1. Flagellates (Intestinal,oral & genital flagellates ):Giardia lamblia,Trichomonastenax,T. hominis.
  1. Flagellates (Intestinal, oral & genital flagellates):
  2. T.vaginalis,Chilomasticmesnili,Dientamoebafragilis
  1. Blood & tissue flagellates :
  2. Visceral leishmaniasis,Cutaneous  leishmaniasis , Mucocutaneousleishmaniasis
  1. Blood & tissue flagellates :
  2. Trypanosomagambiense ,T. rhodesiense, T. cruzi
  1. Sporozoa :Malaria Parasite ,Babesia.
  1. Sporozoa :Toxoplasma gondii ,Isospora belli , Cryptosporidium  parvum, Sarcocystis,Blastocystishominis,Pnemocystisjirovecii
  2. Ciliophora :Balantidium coli
  1. Medical Entomology

Practical Sessions:

  1. Introduction,faecal examination
  1. Enterobius,Trichuris.Strongyloides, Ascaris
  1. Hookworms
  1. Echinococcus  spp.
  1. Trichinella , Filaria,larvamigrans,
  1. Schistosoma
  1. Cultivation of helminthes  Preservation of helminthes.
  1. Blood film and stool examination
  1. Introduction, faecal examination, Entamoeba. Other amoebae       
  1. Flagellates, ciliates
  1. Culture methods used in Protozoology.
  1. Leishmania, Trypanosoma.
  2. Malaria (Plasmodium)
  1. Preservation of protozoa
  1. Animal inoculation as a method of diagnosis. Staining method.
  1. Medical  Insects

Medical Mycology
Second Course:
Credits: 3 credit = (2 hr theory lectures+ 2 hr practical)/week

  1. Superficial Mycosis: Dermatophytosis, Keratomycosis, Malassezia spp., TineaNigra, &Piedra.
  1. Subcutaneous mycosis:Lobomycosis, Mycetoma, Sporotrichosis, &Chromoblastomycosis.
  1. Deep Mycosis: Aspergillosis, Blastomycosis.
  1. Candidiasis
  1. Coccidoidomycosis, Cryptococcosis
  1. Histoplasmosis&Pneumocystosis
  1. Penicillosis, &Protothecosis
  1. Fungal infection among AIDS patients.
  1. Antimycotic therapy
  1. Mycotoxicosis
  1. Lab. Dx. Of fungal infection
  1. Topics presented by students

Practical Sessions

  1. Data show of theoretical  related fungal infection
  1. Data show of theoretical  related fungal infection
  1. Data show of theoretical  related fungal infection
  1. Data show of theoretical  related fungal infection
  1. Data show of theoretical  related fungal infection
  1. Data show of theoretical  related fungal infection
  1. Data show of theoretical  related fungal infection
  1. Data show of theoretical  related fungal infection

Molecular Biology Curriculum for PhD students
Credits: 2 units: 2 theory lectures /week

1. Introduction
-DNA replication
-Mechanisms of replication
-Telomeres and telomerase

2. Gene expression introduction:
- Mechanisms of gene expression
- Gene expression control for eukaryotics and prokaryotics
- Post-translational proteins folding
- Operons

3.  Microbial genetics introduction
- Concept ofallelic variation
- The in-lab auxotrophic and prototrophic selection of mutant cells
-Transformation – Conjugation-Transduction
-Chromosomal mapping in bacteria and in bacteriophages

4. Molecular biology applications and tests (introduction)
5.  Gel electrophoresis – RFLP-PFGE
6.  Restriction endonucleases
7.  Hybridization techniques

8.  Microarrays
9.  Gene cloning

10.  PCR principles
11.  Traditional PCR mechanisms
12.  Traditional PCR optimization (full set of maneuvers)
13. Real-time PCR
- Quantification using real-time PCR
- Reverse transcriptase real-time PCR

14.Mutation detection techniques

15.DNA methylation and gene expression regulation

16.Genomic imprinting

17.Protein non-coding RNAs

18.Genetic variation and DNA markers

19.Introduction to Cytogenetic and Cytogenetic abnormalities

20.Molecular biology of Mitochondrial DNA